Sunday 18 August 2013

Facts about N-Carbethoxy-4-piperidone

N-Carbethoxy-4-piperidone is one of the derivatives of N-Methyl Piperidone derivatives . New and affordable intermediates are being developed by manufacturers who are keen to deliver outstanding support and value to the customers. Other such chemicals under this derivative are N-Methyl-4-Hydroxy piperidine, N-Carbethoxy-4-Amino piperidine, N-Carbethoxy-4-Hydroxy piperidine, N-Carbethoxy-4-piperidone, N-Methyl-4-Amino piperidine, N-Methyl-4-Chloro piperidine and N-Methyl-4-Hydroxy piperidine. The manufacturing and preparation of this derivative are the results of an intensive research which can be utilized as bulk intermediates in various industries and laboratory researches. The demand for such derivatives has created zeal amongst the chemical researchers. 



The Piperidone  derivative N-Carbethoxy-4-piperidone appear to be clear colourless which can vary up to pale yellow colored liquid. This is basically the chemical name by which the general manufacturers and the customers refer to. Chemicals are produced in the same way all over the globe with the support of the same preparation process and chemical reactions. The only thing which differs is the availability of the raw materials in abundance so as to satisfy the demands of the customers. Penfluridol is utilized as a raw material in the manufacturing of the product. The other preparatory product which is of great value is 4-(2-Keto-1-Benzimidazolinyl piperidine). 


The other names by which N-Carbethoxy-4-piperidone are known as N-ETHOXYCARBONYL-4-PIPERIDONE, N-Carbethoxy-4-Piperidone99%, N-CARBOETHOXY-4-PIPERIDONE, N-Carbithoxy-4-Piperidone, 1-CARBETHOXY-4-PIPERIDONE, N-CARBETHOXY-4-PIPERIDONE, carbethoxy-4-piperidone, N-Carbethoxypiperidone, AURORA KA-3057. This chemical product is represented by the molecular formula C8H13NO3. The IUPAC name by which it is identified is ethyl 4-oxopiperidine-1-carboxylate

The salient features are:

  •     Formula weight: 171.19
  •     Boiling point: 95 to 98 degree Celsius ( 1 mmHg)
  •     Refractive Index: n20/D 1.475 (lit.)
  •     Flashing point: 190 degree Fahrenheit
  •     MOL File: 29976-53-2 mol
  •     H-Bond donor: 0
  •     H-Bond acceptor: 3
  •     Exact mass: 171.08
  •     Mono Isotropic mass: 171.08
  •     Complexity: 181
  •     Formal charge: 0
  •     Topological polar surface area: 56.6

Uses:

This is utilized in the preparatory procedure of N-Methyl-4-piperidone which are identified as antihypertensive agents, and ?-carboline derivatives as potential serotonergic agents. This chemical product can also be utilized as an impurity of Loratadine.

This derivative is slightly soluble in water and has been tested as an irritant which is one of the hazardous notes for all the customers to be aware as a precautionary which needs to be kept in consideration while using the chemical. The chemical can be synthesized in a customized way depending on the requirement and specifications of the clients.  This N-Carbethoxy-4-piperidone are fine intermediate chemicals whose range product categories are pharmaceutical intermediates, piperidones, piperazines, pipeiridines, boronic acid and heterocyclic compounds.

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